Promising Malaria Drug Has a Putting Downside: Blue Urine

Promising Malaria Drug Has a Putting Downside: Blue Urine


An Anopheles mosquito, which might carry malaria, in Mali throughout an experiment. A therapy in West Africa has been discovered to be efficient in opposition to malaria however occurs additionally to show a affected person’s urine blue.

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Fabien Beilhe

Assessments in West Africa have discovered that a secure drug lengthy used to deal with urinary tract infections can be efficient in opposition to malaria. However the medicine has one drawback: it turns urine a vivid blue.

“That is one thing we have to clear up, as a result of it might cease folks from utilizing it,” mentioned Teun Bousema, a microbiologist at Radboud College Medical Heart within the Netherlands and an writer of the study, which was printed Tuesday in The Lancet Infectious Ailments.

Fashionable malaria therapies, primarily based on the drug artemisinin, are nonetheless efficient in Africa and save a whole lot of 1000’s of lives every year. However scientists concern the parasites will develop resistance, as they have in Southeast Asia, and are searching for methods to kill them sooner utilizing cocktails of a number of medicine.

Methylene blue, a dye used to stain tissues considered underneath a microscope, will be taken by pill or injection, and is usually used to deal with urethral infections and a hemoglobin dysfunction.

However the dye additionally kills the malaria parasites within the gametocyte stage, the purpose at which mosquitoes decide it up from human blood and go it on to new victims.

Most malaria medicine don’t goal gametocytes, that means that somebody should unfold the illness for every week or extra after therapy.

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